Human SLITRK6 Protein (His Tag)
DFNMYP,SLITRK6
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| Catalog Number | P13922-H08H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | DFNMYP,SLITRK6 |
| Molecular Weight | The recombinant human SLITRK6 consists of 593 amino acids and predicts a molecular mass of 62.2 KDa. It migrates as an approximately 89 KDa band in SDS-PAGE under reducing conditions. |
| predicted N | Ser 27 |
| SDS-PAGE |  |
| Purity | > 85 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human SLITRK6 (Q9H5Y7) (Met1-Ser608) was expressed with a polyhistidine tag at the C-terminus. |
| Bio-activity | |
| Research Area | Signaling |Signal Transduction |Second Messenger |Nucleotide Messenger |GTP |
| Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | SLITRK6 belongs to the SLITRK family. Members of this family share two conserved leucine-rich repeat domains in the extracellular domain. SLITRK6 contains 11 LRR (leucine-rich) repeats, 2 LRRCT domains and 2 LRRNT domains. Expression of SlITRK proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. SLITRK6 is highly expressed in putamen with no expression in cerebral cortex. It also can be detected in adult and fetal lung and fetal liver. It can suppresse neurite outgrowth. In adult brain, SLITRK6 has a critical role in the development of the inner ear neural circuit. |
| Reference |