Human Semaphorin 4A / SEMA4A / Semaphorin B Protein (Fc Tag)
CORD10,RP35,SEMAB,SEMB
- 100ug (NPP2487) Please inquiry
Catalog Number | P11756-H02H |
---|---|
Organism Species | Human |
Host | Human Cells |
Synonyms | CORD10,RP35,SEMAB,SEMB |
Molecular Weight | The secreted recombinant human SEMA4A/Fc chimera is a disulfide-linked homodimer. The reduced monomer consists of 893 amino acids and predictes a molecular mass of 99 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh SEMA4A/Fc monomer is approximately 110 kDa due to glycosylation. |
predicted N | Gly 32 |
SDS-PAGE | |
Purity | > 90 % as determined by SDS-PAGE |
Protein Construction | A DNA sequence encoding the human SEMA4A (NP_071762.2) extracellular domain (Met 1-His 683) was fused with the Fc region of human IgG1 at the C-terminus. |
Bio-activity | Measured by its ability to bind mouse SEMA4D in a functional ELISA. |
Research Area | Cancer |Invasion microenvironment |Angiogenesis |Angiogenesis Inhibitor |
Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Background | |
Reference |