Human Statherin / STATH Protein (Fc Tag)
STATH,STR
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| Catalog Number | P13694-H05H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | STATH,STR |
| Molecular Weight | The recombinant human STATH/mFc is a disulfide-linked homodimer. The reduced monomer comprises 277 amino acids and has a predicted molecular mass of 31.6 kDa. The apparent molecular mass of the protein is approximately 36 in SDS-PAGE under reducing conditions. |
| predicted N | Asp 20 |
| SDS-PAGE |  |
| Purity | > 95 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human STATH (P02808-1) (Met1-Phe62) was fused with Fc region of mouse IgG at the C-terminus. |
| Bio-activity | |
| Research Area | |
| Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | Statherin, also known as STATH, belongs to the histatin/statherin family. Statherin may play an important role in the maintenance of oral health.It prevents calcium phospate precipitation in saliva, so maintaining a high calcium level in saliva and preventing teeth from dissolving. Statherin also inhibits spontaneous precipitation of calcium phosphate salts. Thus, statherin and PRPs may prevent build-up of harmful deposits in the salivary glands and on the tooth surfaces.Statherin is a highly stable salivary protein of low molecular mass (5,380). Sabatini et al. synthesized mixed oligonucleotides based on the known amino acid sequence of statherin and used these to screen a cDNA library constructed from human parotid gland mRNA. |
| Reference |