Human TALLA-1 / TSPAN7 Protein (His Tag)
A15,CCG-B7,CD231,DXS1692E,MRX58,MXS1,TALLA-1,TM4SF2,TM4SF2b
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Catalog Number | P14031-H08H |
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Organism Species | Human |
Host | Human Cells |
Synonyms | A15,CCG-B7,CD231,DXS1692E,MRX58,MXS1,TALLA-1,TM4SF2,TM4SF2b |
Molecular Weight | The recombinant human TSPAN7 consists of 112 amino acids and predicts a molecular mass of 13 KDa. It migrates as an approximately 24-30 KDa band in SDS-PAGE under reducing conditions. |
predicted N | Arg 113 |
SDS-PAGE | |
Purity | > 95 % as determined by SDS-PAGE |
Protein Construction | A DNA sequence encoding the human TSPAN7 (AAH08429.1) (Arg113-Met213) was expressed with a polyhistidine tag at the C-terminus. |
Bio-activity | |
Research Area | Signaling |Signal Transduction |Metabolism |Pathways and Processes |Metabolic signaling pathways |Amino acid metabolism | |
Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Background | TALLA-1, also known as TSPAN7, is a member of the transmembrane 4 superfamily Most members of this family are cell-surface proteins that are characterized by the presence of four hydrophobic domains. TALLA-1 gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. TALLA-1 is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. |
Reference |