Human TXNRD1 / TRXR1 Protein (aa 161-647, His Tag)

GRIM-12,TR,TR1,TRXR1,TXNR

Catalog Number	P13093-H07E
Organism Species	Human
Host	E. coli
Synonyms	GRIM-12,TR,TR1,TRXR1,TXNR
Molecular Weight	The recombinant human TXNRD1 consisting of 498 amino acids and has a calculated molecular mass of 55 kDa. It migrates as an 60 kDa band in SDS-PAGE under reducing conditions as predicted.
predicted N	Met
SDS-PAGE
Purity	> 90 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the human TXNRD1 isoform 1 (Q16881-1) (Tyr 161-Cys 647) was expressed, with a polyhistide tag at the N-terminus.
Bio-activity
Research Area	Cancer \|Signal transduction \|Metabolism \|Types of disease \|Metabolism in Cancer
Formulation	Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Gasdaska P.Y., et al., 1995, FEBS Lett. 373:5-9. Rundloef A.-K., et al., 2004, Free Radic. Biol. Med. 36:641-656. Rikova K., et al., 2007, Cell 131:1190-1203. Fritz-Wolf K., et al., 2007, J. Mol. Biol. 370:116-127. Choudhary C., et al., 2009, Science 325:834-840.