Human VSTM1 Protein (Fc Tag)
SIRL-1,SIRL1,UNQ3033
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| Catalog Number | P13171-H02H |
|---|---|
| Organism Species | Human |
| Host | Human Cells |
| Synonyms | SIRL-1,SIRL1,UNQ3033 |
| Molecular Weight | The recombinant human VSTM1/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 360 amino acids and has a predicted molecular mass of 40.6 kDa. The apparent molecular mass of the reduced monomer is approximately 50-60 kDa in SDS-PAGE under reducing conditions. |
| predicted N | Tyr 17 |
| SDS-PAGE |  |
| Purity | > 90 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the human VSTM1 (Q6UX27-16) extracellular domain (Met 1-Thr 135) was fused with the Fc region of human IgG1 at the C-terminus. |
| Bio-activity | |
| Research Area | Cancer |Signal transduction |Hormones |
| Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | V-set and transmembrane domain containing 1 (VSTM1) is a protein containing the V-set domains. V-set domains are immunoglobulin-like domains resembling the antibody variable region. V-set domains are found in many kinds of protein families, including immunoglobulin light and heavy chains, several T-cells such as CD2, CD4, CD80, and CD86, myelin membrane adhesion molecules, junction adhesion molecules (JAM), tyrosine-protein kinase receptors, and the programmed cell death protein1. |
| Reference |