Human XCL1 Protein (His Tag)

ATAC,LPTN,LTN,SCM-1,SCM-1a,SCM1,SCM1A,SCYC1

Catalog Number	P10672-H08B
Organism Species	Human
Host	Baculovirus-Insect Cells
Synonyms	ATAC,LPTN,LTN,SCM-1,SCM-1a,SCM1,SCM1A,SCYC1
Molecular Weight	The recombinant human XCL1 consists of 103 amino acids and predicts a molecular mass of 11.6 kDa. The apparent molecular mass of rhXCL1 is approximately 15-20 kDa in SDS-PAGE under reducing conditions.
predicted N	Val 22
SDS-PAGE
Purity	> 85 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the human XCL1 (P47992) (Met 1-Gly 114) was expressed, fused with a polyhistidine tag at the C-terminus.
Bio-activity
Research Area	Immunology \|Inflammation / Inflammatory Mediator \|Inflammatory Cytokines & Chemoki and Receptors \|Chemokines and Receptors \|C Chemokines and Receptors
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Nguyen KD, et al. (2008) XCL1 enhances regulatory activities of CD4⁺ CD25(high) CD127(low/-) T cells in human allergic asthma. J Immunol. 181 (8): 5386-95. Dong C, et al. (2005) Glycosylated recombinant human XCL1 / lymphotactin exhibits enhanced biologic activity. J Immunol Methods. 302 (1-2): 136-44. Zavala-Flores LM, et al. (2009) Production of biologically active human lymphotactin (XCL1) by Lactococcus lactis. Biotechnol Lett. 31 (2): 215-20.