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Influenza A H10N8 (A/duck/Guangdong/E1/2012) Neuraminidase / NA Protein (His Tag)

NA,Neuraminidase

Catalog Number P40352-V07B
Organism Species H10N8
Host Baculovirus-Insect Cells
Synonyms NA,Neuraminidase
Molecular Weight The recombinant Neuraminidase of Influenza A virus (A/duck/Guangdong/E1/2012(H10N8)) consists 449 amino acids and predicts a molecular mass of 50.2 kDa.
predicted N His
SDS-PAGE
Purity > 95 % as determined by SDS-PAGE.
Protein Construction A DNA sequence encoding the Influenza A virus (A/duck/Guangdong/E1/2012(H10N8)) Neuraminidase (AFJ19054.1) (Gly38-Gly470) was expressed with a polyhistidine tag at the N-terminus.
Bio-activity
Research Area Microbiology |Pathogenic microorganism |viruses |animal virus |viral illness |Viral tract respiratory illness |
Formulation Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 8.0.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the host cell.
Reference
  • Sardet C., et al.,(1989), Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter. Cell 56:271-280.
  • Sardet C., et al., (1990), Growth factors induce phosphorylation of the Na+/H+ antiporter, glycoprotein of 110 kD.Science 247:723-726.
  • Tse C.-M., et al.,(1991), Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger.EMBO J. 10:1957-1967.