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Influenza A H1N3 (A/duck/NZL/160/1976) Hemagglutinin / HA Protein (His Tag)

HA

Catalog Number P11685-V08H
Organism Species H1N3
Host Human Cells
Synonyms HA
Molecular Weight The recombinant influenza A H1N3 (A/duck/NZL/160/1976 (H1N3)) HA comprises 523 amino acids and has a predicted molecular mass of 59 kDa.
predicted N Asp 18
SDS-PAGE
Purity > 95 % as determined by SDS-PAGE
Protein Construction A DNA sequence encoding the extracellular domain (Met 1-Gln 529) of the influenza A Hemagglutinin (A/duck/NZL/160/1976 (H1N3)) (ABB20429.1) (HA1+HA2, uncleaved) was expressed, fused with a C-terminal polyhistidine tag.
Bio-activity Measured by its ability to agglutinate human red blood cells.
HA titer is 10-40 μg/mL for 1% HRBC.
Research Area Microbiology |Pathogenic microorganism |viruses |animal virus |viral illness |Viral tract respiratory illness |
Formulation Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference
  • White JM, Hoffman LR, Arevalo JH, et al. (1997). "Attachment and entry of influenza virus into host cells. Pivotal roles of hemagglutinin". In Chiu W, Burnett RM, Garcea RL. Structural Biology of Viruses.
  • Suzuki Y (March 2005). "Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses". Biol. Pharm. Bull. 28 (3): 399–408.
  • Senne DA, Panigrahy B, Kawaoka Y, et al. (1996). "Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential". Avian Dis. 40 (2): 425–37