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Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase / NA (His Tag)

NA

Catalog Number P40199-V07H
Organism Species H3N2
Host Human Cells
Synonyms NA
Molecular Weight The recombinant neuraminidase of Influenza A virus (A/Aichi/2/1968 (H3N2)) comprises 453 amino acids and has a predicted molecular mass of 50.8 kDa. The apparent molecular mass of the protein is approximately 76.8 kDa in SDS-PAGE under reducing conditions.
predicted N His
SDS-PAGE
Purity > 90 % as determined by SDS-PAGE
Protein Construction A DNA sequence encoding the Influenza A virus (A/Aichi/2/1968(H3N2)) neuraminidase (Q75VQ4.1) (His36-Ile469) was expressed with a N-terminal polyhistidine tag.
Bio-activity
Research Area Microbiology |Pathogenic microorganism |viruses |animal virus |viral illness |Viral tract respiratory illness |
Formulation Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the host cell.
Reference
  • Sardet C., et al.,(1989), Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter. Cell 56:271-280.
  • Sardet C., et al., (1990), Growth factors induce phosphorylation of the Na+/H+ antiporter, glycoprotein of 110 kD.Science 247:723-726.
  • Tse C.-M., et al.,(1991), Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger.EMBO J. 10:1957-1967.