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Influenza A H3N2 (A/Babol/36/2005) Neuraminidase / NA (His Tag)

NA

Catalog Number P40017-V07H
Organism Species H3N2
Host Human Cells
Synonyms NA
Molecular Weight The recombinant influenza H3N2 virus neuraminidase (A/Babol/36/2005 (H3N2)) comprises 443 amino acids and has a predicted molecular mass of 49.6 kDa. The apparent molecular mass of the recombinant protein is approximately 80 kDa in SDS-PAGE under reducing conditions due to glycosylation.
predicted N His
SDS-PAGE
Purity > 90 % as determined by SDS-PAGE
Protein Construction A DNA sequence encoding the Influenza A H3N2 virus (A/Babol/36/2005) Neuraminidase (ACN50232.1) (His 36-Pro 459) was fused with a polyhistidine tag at the N-terminus.
Bio-activity
Research Area Microbiology |Pathogenic microorganism |viruses |animal virus |viral illness |Viral tract respiratory illness |
Formulation Lyophilized from sterile PBS, pH 7.4
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the host cell.
Reference
  • Sardet C., et al.,(1989), Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter. Cell 56:271-280.
  • Sardet C., et al., (1990), Growth factors induce phosphorylation of the Na+/H+ antiporter, glycoprotein of 110 kD.Science 247:723-726.
  • Tse C.-M., et al.,(1991), Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger.EMBO J. 10:1957-1967.