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Influenza A H5N8 (A/broiler duck/Korea/Buan2/2014(Buan2)) Hemagglutinin / HA1 Protein (His Tag)

Hemagglutinin, HA1

Catalog Number P40384-V08H2
Organism Species H5N8
Host Human Cells
Synonyms Hemagglutinin, HA1
Molecular Weight The recombinant HA1 subunit of the Influenza A virus (A/broiler duck/Korea/Buan2/2014(H5N8)) hemagglutinin consists of 340 amino acids and predicts a molecular mass of 38.8 kDa.
predicted N Asp 17
SDS-PAGE
Purity > 90 % as determined by SDS-PAGE.
Protein Construction A DNA sequence encoding the Influenza A virus (A/broiler duck/Korea/Buan2/2014(H5N8)) hemagglutinin (AHL21407.1) (Met1-Arg345), termed as HA1, was expressed with a polyhistidine tag at the C-terminus.
Bio-activity
Research Area Microbiology |Pathogenic microorganism |viruses |animal virus |viral illness |Viral tract respiratory illness |
Formulation Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference
  • White JM, Hoffman LR, Arevalo JH, et al. (1997). "Attachment and entry of influenza virus into host cells. Pivotal roles of hemagglutinin". In Chiu W, Burnett RM, Garcea RL. Structural Biology of Viruses.
  • Suzuki Y (March 2005). "Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses". Biol. Pharm. Bull. 28 (3): 399–408.
  • Senne DA, Panigrahy B, Kawaoka Y, et al. (1996). "Survey of the hemagglutinin (HA) cleavage site sequence of H5 and H7 avian influenza viruses: amino acid sequence at the HA cleavage site as a marker of pathogenicity potential". Avian Dis. 40 (2): 425–37