Mouse APLP1 / Amyloid-like Protein (His Tag)
Aplp1
- 100ug (NPP2748) Please inquiry
Catalog Number | P51730-M08H |
---|---|
Organism Species | Mouse |
Host | Human Cells |
Synonyms | Aplp1 |
Molecular Weight | The recombinant mouse Aplp1 consists of 557 amino acids and predicts a molecular mass of 62.4 kDa. |
predicted N | Asn 39 |
SDS-PAGE | |
Purity | > 95 % as determined by SDS-PAGE. |
Protein Construction | A DNA sequence encoding the mouse Aplp1 (NP_031493.2) (Met1-Glu584) was expressed with a polyhistidine tag at the C-terminus. |
Bio-activity | |
Research Area | Immunology |Signal Transduction |Other Signal Transduction Molecules |
Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Background | APLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease. |
Reference |