Mouse Anti-Human CD255

100ug (NP20046) Please inquiry

Antibody type:Flowcytometry

Label:Unconjugated

Modification:Unmodification

Isotype:IgG3

Host:Mouse

Application:FCM

Purify method:

Species:Human

Gene Name:

Synonyms:

Gene Synonyms:

Gene Full Name:

Gene Infomation:

Antigen:

Antigen Synonyms:

Clonality:

Source:

Reaction:

Form:Liquid

Tested Applications:

Western blot (1:100 to 1:500)
Immunofluorescence (1:50 to 1:400)
Immunohistochemistry (1:200 to 1:500)
Flow cytometry analysis (1:200 to 1:500)
Enzyme-linked Immunosorbent Assay (1:100-1:5000)

Note: Users are strongly advised to determine the optimal dilution of antibody to use for their specific applications.

Clone:7F7-G1

Dilution:

Mole Mass:

Location:

Concentration:

Sequence Similarity:

Gene Id:

SwissProt ID:

Unigene:

Nucleotide Accession:

Tissue specificity:

Storage:短期内经常使用时，请将抗体2-8℃保存，至少可以保存6个月。若长期保存，请将抗体分装后-20℃至-80℃保存，切忌反复冻融。

Buffer condition:0.01M PBS,0.09% NaN3,pH7.4

Background:相关介绍：肿瘤坏死因子样凋亡微弱诱导剂(TNF-like weak inducer of apoptosis，TWEAK)，作为TNF配体家族成员之一，为Ⅱ型跨膜蛋白，其胞外部分有很高的的同源性，又被称为CD255。TWEAK转录产物广泛表达在成人和胚胎组织中，然而，在外周血中单核细胞也能够和TWEAK特异性抗体结合。TWEAK是和细胞膜结合，以分泌形式表达，其与受体（DR3;Fn14）相互作用能够促进IL-8的分泌，激活NF-κB，内皮细胞的增殖以及人细胞系的凋亡。CD255抗体（克隆号：4ACARL-2）能够中和重组蛋白TWEAK的生物活性。

Molar Function:肿瘤坏死因子样凋亡微弱诱导剂(TNF-like weak inducer of apoptosis，TWEAK)，作为TNF配体家族成员之一，为Ⅱ型跨膜蛋白，其胞外部分有很高的的同源性，又被称为CD255。TWEAK转录产物广泛表达在成人和胚胎组织中，然而，在外周血中单核细胞也能够和TWEAK特异性抗体结合。TWEAK是和细胞膜结合，以分泌形式表达，其与受体（DR3;Fn14）相互作用能够促进IL-8的分泌，激活NF-κB，内皮细胞的增殖以及人细胞系的凋亡。CD255抗体（克隆号：7F7-G1）能够中和重组蛋白TWEAK的生物活性。

Western Blot:

Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.