Mouse Anti-Human CD326
- 100ug (NP20042) Please inquiry
Antibody type:Flowcytometry
Label:Unconjugated
Modification:Unmodification
Isotype:IgG1
Host:Mouse
Application:FCM,IHC,WB
Purify method:
Species:Human
Gene Name:
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Gene Infomation:
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Clonality:
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Reaction:
Form:Liquid
Tested Applications:
- Western blot (1:100 to 1:500)
- Immunofluorescence (1:50 to 1:400)
- Immunohistochemistry (1:200 to 1:500)
- Flow cytometry analysis (1:200 to 1:500)
- Enzyme-linked Immunosorbent Assay (1:100-1:5000)
Clone:6D9-H7
Dilution:
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Sequence Similarity:
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Storage:短期内经常使用时,请将抗体2-8℃保存,至少可以保存6个月。若长期保存,请将抗体分装后-20℃至-80℃保存,切忌反复冻融。
Buffer condition:0.01M PBS,0.09% NaN3,pH7.4
Background:CD326,又称为 Ep-CAM,肿瘤相关钙信号转导蛋白-1基因、上皮细胞表面抗原、上皮糖蛋白2(EGP2)、TROP1等;CD326是I型跨膜蛋白,包含六个二硫键和一个THYRO域,这种细胞表面糖基化,分子量为40kD蛋白在骨髓,结肠癌、肺癌和正常的上皮细胞高度表达,在胃肠道癌病变区也有高表达。近期,据报道,CD326在红细胞生成的早期就有表达,其功能是作为同型依赖性钙离子细胞粘附分子,同时被认为是能够诱导基因在细胞代谢和增殖过程中致癌的。
Molar Function:CD326,又称为 Ep-CAM,肿瘤相关钙信号转导蛋白-1基因、上皮细胞表面抗原、上皮糖蛋白2(EGP2)、TROP1等;CD326是I型跨膜蛋白,包含六个二硫键和一个THYRO域,这种细胞表面糖基化,分子量为40kD蛋白在骨髓,结肠癌、肺癌和正常的上皮细胞高度表达,在胃肠道癌病变区也有高表达。近期,据报道,CD326在红细胞生成的早期就有表达,其功能是作为同型依赖性钙离子细胞粘附分子,同时被认为是能够诱导基因在细胞代谢和增殖过程中致癌的。
Western Blot:Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.