Mouse CHL-1 Protein
A530023M13Rik,AI465420,CALL,LICAM2
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| Catalog Number | P51176-MCCH |
|---|---|
| Organism Species | Mouse |
| Host | Human Cells |
| Synonyms | A530023M13Rik,AI465420,CALL,LICAM2 |
| Molecular Weight | The recombinant mouse CHL1 comprises 1010 amino acids and has a predicted molecular mass of 113.3 kDa. The apparent molecular mass of the protein is approximately 113-123 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
| predicted N | Ala 25 |
| SDS-PAGE |  |
| Purity | > 90 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the mouse CHL1 (Met1-Gln1027) was expressed with six amino acids (LEVLFQ) at the C-terminus. |
| Bio-activity | |
| Research Area | Neuroscience |Cell Adhesion Proteins |Membrane Proteins |
| Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | Neural cell adhesion molecule L1-like protein, also known as close homolog of L1 (CHL1) is the prototypic member of the CTF / NF-1 family of transcription factors that serve as a novel calcium signaling pathway-responsive transcription factor and is considered as a member of the largest ctf complementation group, consisting of 30 of 126 ctf mutants isolated. CHL1 is a cell adhesion molecule highly related to L1. It contains structure plan of six extracellular C2-type immunoglobulin (Ig) domains followed by five fibronectin typeⅢ domains linked by a single membrane-spanning region to a short cytoplasmic domain. The extracellular portion of CHL1 is higyly glycosylated and involved them in hemophilic disease. |
| Reference |