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Mouse IFNA13 / Interferon alpha-13 Protein (His Tag)

RP23-139P14.1

Catalog Number P50670-M08H
Organism Species Mouse
Host Human Cells
Synonyms RP23-139P14.1
Molecular Weight The recombinant mouse IFNA13 comprises 177 amino acids and has a predicted molecular mass of 20.5 kDa. The apparent molecular mass of the protein is approximately 26-31 kDa in SDS-PAGE under reducing conditions.
predicted N Cys 24
SDS-PAGE
Purity > 90 % as determined by SDS-PAGE
Protein Construction A DNA sequence encoding the mouse IFNA13 (Q80SU4) (Met1-Glu189) was expressed with a C-terminal polyhistidine tag.
Bio-activity Measured in antiviral assay using L929 cells infected with vesicular stomatitisvirus (VSV).
The ED50 for this effect is typically 10-80 pg/mL.
Research Area Cardiovascular |Angiogenesis |Cytokines / Chemokines in Angiogenesis |Interferons
Formulation Lyophilized from sterile PBS, pH 7.4.
1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference
  • Mahmutovic S, et al.. (2004) Significance of the interferon (IFN) in the therapy. Bosn J Basic Med Sci. 4(4): 42-4.
  • Wang, et al.. (2004) Fever of recombinant human interferon-alpha is mediated by opioid domain interaction with opioid receptor inducing prostaglandin E2. J Neuroimmunol. 156(1-2): 107-12.