Mouse PKC delta / PRKCD Protein (His & GST Tag)

AI385711,D14Ertd420e,Pkcd,PKCdelta,PKC[d]

Catalog Number	P50345-M20B
Organism Species	Mouse
Host	Baculovirus-Insect Cells
Synonyms	AI385711,D14Ertd420e,Pkcd,PKCdelta,PKC[d]
Molecular Weight	The recombinant mouse PRKCD/GST chimera consists of 912 amino acids and has a calculated molecular mass of 106 kDa as estimated in SDS-PAGE under reducing conditions.
predicted N	Met
SDS-PAGE
Purity	> 93 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the mouse PRKCD isoform 1 (P28867-1) (Met 1-Ile 674) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Bio-activity	Kinase activity untested
Research Area	Immunology \|Signal Transduction \|Jak/STAT Signaling \|Positive Regulators of the Jak/STAT Pathway
Formulation	Supplied as sterile 20mM Tris, 500mM NaCl, pH 8.0 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Cross T, et al. (2000) PKC-delta is an apoptotic lamin kinase. Oncogene. 19(19): 2331-7. Song JS, et al. (1998) Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta. Oncogene. 16(26): 3357-68. Shanmugam M, et al. (1998) Association of PKC delta and active Src in PMA-treated MCF-7 human breast cancer cells. Oncogene. 16(13): 1649-54.