Mouse Resistin / ADSF / RETN Protein (Fc Tag)

ADSF,Fizz3,Rstn,Xcp4

Catalog Number	P50488-M01H
Organism Species	Mouse
Host	Human Cells
Synonyms	ADSF,Fizz3,Rstn,Xcp4
Molecular Weight	The recombinant mouse RETN/Fc is a disulfide-linked homodimer. The reduced monomer comprises 354 amino acids and has a calculated molecular mass of 38.6 kDa. The apparent molecular mass of the monomer is approximately 40 kDa in SDS-PAGE under reducing conditions.
predicted N	Glu
SDS-PAGE
Purity	> 80 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the mouse RETN (Q99P87) (Ser 21-Ser 114) was fused with the Fc region of human IgG1 at the N-terminus.
Bio-activity
Research Area	Signaling \|Signal Transduction \|Metabolism \|Pathways and Processes \|Vitamins / minerals
Formulation	Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Verma S, et al. (2003) Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. Circulation. 108(6):736-40. Reilly MP, et al. (2005) Resistin is an inflammatory marker of atherosclerosis in humans. Circulation. 111(7):932-9. Steppan CM, et al. (2002) Resistin and obesity-associated insulin resistance. Trends Endocrinol Metab. 13(1):18-23.