Mouse XCL1 Protein (His Tag)

AI661682,ATAC,Lptn,LTN,SCM-1,SCM-1a,Scyc1

Catalog Number	P50677-M08B
Organism Species	Mouse
Host	Baculovirus-Insect Cells
Synonyms	AI661682,ATAC,Lptn,LTN,SCM-1,SCM-1a,Scyc1
Molecular Weight	The secreted recombinant mouse XCL1 consists of 103 amino acids and has a calculated molecular mass of 11.5 kDa. It migrates as an approximately 20 kDa band in SDS-PAGE under reducing conditions.
predicted N	Val 22
SDS-PAGE
Purity	> 80 % as determined by SDS-PAGE
Protein Construction	A DNA sequence encoding the mouse XCL1 (P47993) (Met 1-Gly 114) was expressed，with a C-terminal polyhistidine tag.
Bio-activity
Research Area	Immunology \|Inflammation / Inflammatory Mediator \|Inflammatory Cytokines & Chemoki and Receptors \|Chemokines and Receptors \|C Chemokines and Receptors
Formulation	Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 7.4, 10% gly 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Background
Reference	Nguyen KD, et al. (2008) XCL1 enhances regulatory activities of CD4⁺ CD25(high) CD127(low/-) T cells in human allergic asthma. J Immunol. 181 (8): 5386-95. Dong C, et al. (2005) Glycosylated recombinant human XCL1 / lymphotactin exhibits enhanced biologic activity. J Immunol Methods. 302 (1-2): 136-44. Zavala-Flores LM, et al. (2009) Production of biologically active human lymphotactin (XCL1) by Lactococcus lactis. Biotechnol Lett. 31 (2): 215-20.