Rat CD48 / SLAMF2 / BCM1 Protein (His Tag)
CD48, Bcm-1
- 100ug (NPP1174) Please inquiry
| Catalog Number | P80286-R08H |
|---|---|
| Organism Species | Rat |
| Host | Human Cells |
| Synonyms | CD48, Bcm-1 |
| Molecular Weight | The recombinant rat CD48 comprises 205 amino acids and predicts a molecular mass of 23.9 kDa. The apparent molecular mass of the recombinant protein is approximately 38-43 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
| predicted N | Phe 23 |
| SDS-PAGE |  |
| Purity | > 95 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the rat CD48 (P10252) (Met1-Arg216) was expressed, fused with a polyhistidine tag at the C-terminus. |
| Bio-activity | |
| Research Area | Immunology |Cluster of Differentiation (CD) |Monocyte/Macrophage CD Antigen |Other Monocytes/Macrophages CD Antigen |
| Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses. |
| Reference |