Rat CD90 / THY-1 Protein (His Tag)
THY1, Thy-1
- 100ug (NPP3133) Please inquiry
Catalog Number | P80337-R08H |
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Organism Species | Rat |
Host | Human Cells |
Synonyms | THY1, Thy-1 |
Molecular Weight | The recombinant rat THY1 comprises 121 amino acids and predicts a molecular mass of 14.1 kDa. The apparent molecular mass of the recombinant protein is approximately 27-29 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
predicted N | Gln 20 |
SDS-PAGE | |
Purity | > 95 % as determined by SDS-PAGE |
Protein Construction | A DNA sequence encoding the rat THY1 (P01830) (Met1-Lys129) was expressed with a polyhistidine tag at the C-terminus. |
Bio-activity | |
Research Area | Developmental Biology |Embryogenesis |Germ Layer Formation |Endoderm Marker |
Formulation | Lyophilized from sterile PBS, pH 7.4 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Background | Mouse Thy-1 membrane glycoprotein, also known as Thy-1 antigen, CD90 and THY1, is a cell membrane protein which contains 1 Ig-like V-type (immunoglobulin-like) domain. It is a glycophosphatidylinositol-linked glycoprotein expressed on the surface of neurons, thymocytes, subsets of fibroblasts, endothelial cells, mesangial cells and some hematopoietic cells. It has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells, and activated endothelial cells. Thy-1 is evolutionarily conserved, developmentally regulated, and often has dramatic effects on cell phenotype. Thy-1 is a 25-37 kDa glycosylphosphatidylinositol (GPI)-anchored protein involved in T cell activation, neurite outgrowth, apoptosis, tumor suppression, wound healing, and fibrosis. To mediate these diverse effects, Thy-1 participates in multiple signaling cascades. Thy-1 is an important regulator of cell-cell and cell-matrix interactions, with important roles in nerve regeneration, metastasis, inflammation, and fibrosis. |
Reference |