Rat CLM-9 / TREM4 / CD300LG Protein (His Tag)
CD300LG
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Catalog Number | P80413-R08H |
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Organism Species | Rat |
Host | Human Cells |
Synonyms | CD300LG |
Molecular Weight | The recombinant rat CD300LG comprises 153 amino acids and predicts a molecular mass of 17.5 kDa. The apparent molecular mass of the recombinant protein is approximately 28 kDa in SDS-PAGE under reducing conditions. |
predicted N | Leu 19 |
SDS-PAGE | |
Purity | > 95 % as determined by SDS-PAGE |
Protein Construction | A DNA sequence encoding the rat CD300LG (XP_002724611.1) (Met1-Arg160) was expressed with a polyhistidine tag at the C-terminus. |
Bio-activity | |
Research Area | Neuroscience |Cell Adhesion Proteins |Cytoskeletal Proteins |Microfilaments |Actin etc |Actin Binding Proteins | |
Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Background | CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM. |
Reference |