Rat Carboxypeptidase A2 / CPA2 Protein (His Tag)
Carboxypeptidase A2,CPA2
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| Catalog Number | P80715-R08H |
|---|---|
| Organism Species | Rat |
| Host | Human Cells |
| Synonyms | Carboxypeptidase A2,CPA2 |
| Molecular Weight | The recombinant rat Cpa2 consists 412 amino acids and predicts a molecular mass of 46.5 kDa. |
| predicted N | Gln 17 |
| SDS-PAGE |  |
| Purity | > 90 % as determined by SDS-PAGE |
| Protein Construction | A DNA sequence encoding the rat Cpa2 (NP_001013101.2) (Met1-Tyr417) was expressed with a polyhistidine tag at the C-terminus. |
| Bio-activity | |
| Research Area | Cancer |Oncoprotein & suppressor & biomarker |Tumor biomarker |Other in cancer biomarker |Globulin |
| Formulation | Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Background | Human Carboxypeptidase A2 ( CPA2 ) is a secreted pancreatic procarboxy -peptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group. The hydrolytic action of CPA2 was identified with a preference towards long substrates with aromatic amino acids in their C-terminal end, particularly tryptophan. CPA2 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. Three different forms of human pancreatic procarboxypeptidase A have been isolated, and the A1 and A2 forms are always secreted as monomeric proteins with different biochemical properties. |
| Reference |